Floyd's son Dan bought Twig's in 1986 to keep it in family hands. Today, it is run by Ben, his wife Annelies, and Ben's brothers Jake and Luke. It employs 20 people, and has annual revenues of around $6.5m (£4.8m).
Rhys urged Americans to mark St David's Day by following the patron saint's motto, "gwnewch y pethau bychain" or "do the little things", on 1 March.
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But at such a busy time of year for hospitals and GP surgeries, appointments and operations are likely to be disrupted for thousands of patients.
# Markdown table output
Author Correction: Myocardial reprogramming by HMGN1 underlies heart defects in trisomy 21